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  1. #21
    Senior Member Rank = Supreme Champion RS2OOO's Avatar
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    The first Fluke Solve treatment was on 13th May - Now 11 days ago.

    As a reminder to save reading previous posts, 12 hours after the first Fluke-Solve treatment and 2 of the 3 fish appeared fully recovered and 1 was still spitting food. After 24 hours all were eating food and not spitting or flashing or yawning. By 30 hours all fish were energetic and lively and appeared 100% fully recovered.


    That status remained until last night when I noticed 1 fish was flashing and spitting food again and another looked a little lethargic. I carried out a 15% water change (around 1100 litres).

    This morning, which is 11 days after the first treatment, I applied the 2nd dose of Fluke-Solve. This is earlier than the 15 days I had planned to wait, but water temps have been higher than expected (18 - 20 C) and therefore, assuming gill flukes, this may have sped up the lifecycle.

    It is 15 hours later but now 2 fish are spitting food and occasional flashing, one of which is quite lethargic and hanging at mid-depth under the pump inlet.

    The improved change in behaviour seemed to start within 12 hours of the first treatment but so far since the 2nd treatment things look to have deteriorated slightly.

    Just been paid so have ordered an Apex Practitioner microscope, but its not going to arrive for another 10 days.

    I hate seeing the fish unwell and feel stupid in assuming a major dealer would only supply fish guaranteed to be clean (He was confident about this too, even suggesting that I don't really need to quarantine his fish).

    In 28 years of breeding my own stock of fish I never once had any kind of illness or parasite (at least any that I've been aware of), and also never had it when buying British bred fish. Only ever had problems with imported fish that I've bought in. Really frustrating.

    Ammonia: 0
    Nitrite: Shows 0 after the suggested 2 minute wait, but goes slightly pink after 5 mins to circa 0.25ppm. Instructions do say to ignore readings after the initial 2 minute wait, but water tested from my old matured tanks stay clear indefinitely.
    PH: 8
    KH: 12 dH

    Praying to see an improvement tomorrow.
    The main concern at present is that the Fluke-Solve claims to remain active for 3 weeks. I have read a study that claims it disappears between 3 days and 2 weeks. If the Fluke-Solve claim is genuinely true, then I shouldn't be seeing a revival of symptoms just 10 / 11 days after treatment.

  2. #22
    Senior Member Rank = Supreme Champion RS2OOO's Avatar
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    Fish seem better and more lively tonight - 36 hours after 2nd treatment.

    Appetites or liveliness not fully back to normal but all fish took food with no noticeable spitting and I've not seen any flashing.

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  4. #23
    Senior Member Rank = Supreme Champion RS2OOO's Avatar
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    As above, after 2nd Fluke-Solve application all fish were back feeding normally and full of vigour and health within 48 hours.

    Today is day 5 following 2nd treatment and whilst all fish are seemingly active and happy, 2 are spitting food again and keep taking pellets but spitting straight back out. (1 of these 2 is a different one to the ones spitting pellets prior to the 2nd treatment and this behaviour started when I fed this morning, just fed again and still the same).

    Not sure what to do next. Microscope not due in post for another Week, but even still, how do you scrape fish that are only 4" long?

    Is the Fluke-Solve still active after 5 days? I'm not convinced it is. I did leave UV on this time, but instructions say this is ok.

    Any ideas?
    Last edited by RS2OOO; 28-05-2018 at 04:16 PM.

  5. #24
    Senior Member Rank = Supreme Champion RS2OOO's Avatar
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    Thought I should come back and update on this.

    By day 7 after 2nd treatment symptoms continued to deteriorate so I added a 3rd dose of fluke-solve.

    2 days later my microscope arrived and 2 koi were still spitting food so I scraped them. Couldn't get any decent amount of mucus from one fish but got some from the 2nd fish and found 2 dead flukes.

    The fact they were there I think means they must have survived at least the 2nd dose but got taken out by the 3rd. (Only 10-20% water changes between doses so theoretically the concentration was increasing each time I dosed.

    It is now; 27 days after 1st dose, 17 days after 2nd dose and 9 days following 3rd dose.

    All symptoms have now gone, all 3 koi eating well and happy, and no flashing or yawning. I intended on re-scraping a couple of days ago but as the fish now seem fine I didn't want to stress them.

    Had some guidance from Fiona (the inventor of fluke-solve), and I showed her the American study claiming Praziquantel breaks down completely as quickly as 3 days after dosing. She said when she tested her product it could still be detected after 6 Weeks with minimal degradation, but the 2nd dose after 21 days is required to maintain levels.

    She is currently working on one case where in a pond environment the Prazi degraded very fast causing the treatment to fail. She is working with an Aquaculture consultant to try and establish the cause.
    Last edited by RS2OOO; 08-06-2018 at 10:16 PM.

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  7. #25
    Extreme Koi Member Rank = Supreme Champion john1's Avatar
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    Glad you are all sorted and fish ok now.
    John

  8. #26
    Glad that it all worked out - and thank you for keeping the forum updated as this is useful information.

 

 
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